Tumor Induction in Germ-free Rats Fed Bracken (Pteridium aquilinumY

نویسندگان

  • Yukiko Sumi
  • Iwao Hirono
  • Shigetoshi Hosaka
  • Ikuko Ueno
  • Masasumi Miyakawa
چکیده

This study indicated that there was no significant difference in the incidence of intestinal tumors between germ-free and conventional rats fed a diet containing bracken, suggesting that gut microflora did not play a definite role in bracken tumorigenesis. However, bracken induced exclusively sarcoma but no adenocarcinoma in germ-free rats, whereas it induced predominantly adenocarcinoma in conventional rats.

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تاریخ انتشار 2006